Best Ergonomic Mouse for Carpal Tunnel

Best Ergonomic Mouse for Carpal Tunnel: Top 8 Picks for 2022

The majority of people spend buck loads of money on improving their CPU case, monitor, GPU, keyboards, etc.

Now consider what other computer input device do you use daily besides the keyboard? You are right; we hardly ever contemplate on the mouse we use. So we should know about all this mouse.

Remember that our wrists have to go through many activities throughout the day. The user with a job that entails continuous computer work is likely to suffer from wrist discomfort.

One such example is carpal tunnel syndrome. It could get worse unless you find the best ergonomic mouse for carpal tunnel syndrome before it spreads onto your arm.

We have picked some of these products that can help you ease the pain during work. Let us have a look.

Need Quick Decision to Select A Product? Just follow This Table



Editor's Rating


 LEKVEY Vertical Wireless Mouse

5 out of 5

Redragon M602 RGB Wired Gaming Mouse

5 out of 5

Logitech MX Master 3 Advanced Wireless Mouse

4.5 out of 5

Jelly Comb Advanced Vertical Wireless Bluetooth Mouse

4 out of 5

Kensington Orbit Trackball Mouse with Scroll Ring

4.5 out of 5

Our Top 8 Best Ergonomic Mouse for Carpal Tunnel

Make sure you choose what you believe will release the pressure and unnecessary movement. Each model is different from the other. So, find the product that can help keep your wrist in a natural position.

1. LEKVEY Vertical Wireless Mouse, Black

This is the best ergonomic mouse for carpal tunnel syndrome with a budget-friendly pricing. While the product may not have a renowned brand name to back up its quality, but it sure packs some high-quality features.

The device is a vertical mouse that has forward/backward buttons on one side. It helps with navigation during browsing and gaming options with less effort.

If you have to work before the computer using a mouse for long hours, we understand the strain your wrist takes. It might not be the RSI issue, but one should not take the risk of overusing the muscle and tendon movements.

Although it is suitable only for right-handed consumers, the handshake position securely contours the hand to the mouse. Consequently, you achieve the most functional yet comfortable operation without posing much wrist pressure.

The unit comes with a 2.4G USB receiver for you to enjoy a seamless connection wirelessly. Plus, the swooping triple sensitivity modes will allow the mouse to fly high without a sweat.

Another positive side of this unit is rechargeable battery integration. While many vertical wireless mice come with batteries that require changing, you will not have to go through such hassle here.

Not only will it enhance work efficiency, but the device will also prevent any sign of carpal tunnel symptoms. To summarize, it is worth looking into.

Highlighted Feature:

  • Vertical design for ergonomic, pressure-free use
  • Three modes of DPI resolution; 800/1200/1600
  • Includes back and forward buttons
  • Built-in battery; rechargeable
  • Wireless via 2.4G USB receiver

2. Redragon M602 RGB Wired Gaming Mouse, Black

Who does not love to own a gaming mouse with RGB lighting to boost the gaming station ambiance? However, the device must also be competent for easing the numbness and pain one struggles with.

The Redragon is a famous brand that many gamers, PC builders have known for quite a while. Thanks to their incredible technological knowledge, the users receive premium featured devices.

Similarly, this mouse is not just ergonomically convenient but also comes with many opportunities. Firstly, it has five DPI resolution that is adjustable to your need. It also offers 10G acceleration.

Now, the fast-paced gaming will give you entirely a new experience with pinpoint accuracy. Secondly, there are seven durable and responsive buttons that nicely profiles the device.

The user can program the five buttons based on the requirements. Additionally, you can distinctly identify each of them with LED backlight color modes.

Finally, it is the comfortability, which this horizontally contoured mouse provides at all times. It fits naturally in any sized hands, allowing wide ranges of people to try out.

Since the buttons are finely tuned, you will hardly feel fatigued during nonstop clicking combat. Remember that this is a wired product. Hence, it might not be the first choice for some.

However, wired mice tend to be more useful than wireless ones for a reliable connection.

Highlighted Features

  • 7 billion RGB color backlight modes
  • 7 MMO programmable buttons
  • 5 adjustable DPI resolution; 800/1200/1600/2400/7200
  • 6-feet, high-speed braided fiber cable; corrosion-free USB connector
  • Anti-skid scroll wheel and built-in weight tuning option

3. Logitech MX Master 3 Advanced Wireless Mouse, Graphite

Most of us have heard of Logitech for quick and easy replacements of PC output devices. Whether it is a keyboard or a mouse, the brand is known for its durable, sturdy products for many years.

So does the MX Master 3 wireless mouse fit into the same category? We will have to say that we were a little disappointed by its size. Although it is suitable for small-handed users, it will bring no comfort to the large palms.

It is certainly an ideal option for creative/artist users who has to work for hours on a computer. Nevertheless, the catch is limited consumer availability.
The device offers a comfortable shape along with intuitive thumb controls despite the small back of the mouse. You can customize its settings according to the specific application you use.

This will enable your work to be more efficient and productive. Our favorite feature is the exceptional scroll wheel speed that is quiet and precise. Another best option is flow cross-computer control.

It allows the user to transfer cursor, files, or texts seamlessly between desktops/laptops. The feature truly is timesaving for the busy bees out there.

Moreover, it is wireless with a USB-C rechargeable option that lasts up to seventy days per charge. Even the 4000 DPI sensor lets you work on a glass surface without any effort.

Though it is somewhat small and difficult for a group of users, we still consider it as an ergonomic mouse for others.

Highlighted Features

  • Ultra-fast MagSpeed scrolling
  • Ability to transfer cursor or files across OS
  • 4000 maximum DPI sensor for 5x more precision
  • Wireless; USB-C rechargeable
  • 6 customizable buttons

4. Jelly Comb Advanced Vertical Wireless Bluetooth Mouse, MV045-Black

This is an advanced and unique design to resolve pain and carpal tunnel syndrome problems. Its unique concave area for the thumb and small extended lower edge for the pinky finger make it more intriguing.

Some might find the handshake structure a little strange at first but will eventually love its ergonomic grip. You can connect the device with the help of a Bluetooth or a 2.4G wireless connection without any hassle.

The three modes of the DPI sensor ensures normal to super-fast sensitivity depending on your activity. It can track smoothly no matter what surface you have underneath the device.

There are six buttons, including the back/forward for quick navigation on the monitor. However, the reason we have chosen this product is for the ultimate comfort it conveys.

If you wish to prevent wrist strain in advance or already struggling with carpal tunnel issues, this mouse will help you tremendously. From the wide compatibility of connection to the reasonable sensibility, you will achieve it all at an affordable price.

This is why it might come as convenient to various users with RSI problems. The handshake position automatically reduces the pain or stress felt in the wrist and forearm.

Now, you will not have to take quick breaks too frequently in between works to relieve the strain. In short, the device will increase your workflow contently.

Highlighted Features

  • 3 DPI sensor; 1000/1600/2400
  • 2.4G USB and BT 4.0 wireless connection
  • Includes forward/backward buttons
  • Handshake design to prevent wrist pain and strain
  • Silent clicks for the uninterrupted work environment5.

5. Kensington Orbit Trackball Mouse with Scroll Ring (K72337US), Black

Here is a trackball mouse for those who have to deal with wrist pain almost daily. It is stationary, comfortable, and optical for precise cursor movement without straining the hand.

It is designed in a way that even left-handed people will benefit from the ambidextrous feature. The device does not really have many functions to discuss.

However, a minimal button design is what makes it more useful in the long run. It offers a medium spherical ball in the center that works like a cursor in the computer. The ring-like dial surrounding the ball can spin flawlessly for scrolling purposes.

You can adjust the cursor and scroll speed as well as assign various functions to the buttons. Of course, it is possible through the brand’s software that the user has to download.

Plus, it comes with a separate wrist rest for additional cushioning. It will cradle the hand in such a position that you will not have to worry about pressure or numbness anymore.

The only drawback is, not many people are used to this kind of mice. So the user must check if he/she can get along with the device. Failing to do so can lead to more discomfort instead of a positive outcome.

So, make sure you can handle the trackball for a longer period.

Highlighted Features

  • 40mm sphere-shaped blue ball for precise tracking control
  • Dial scroll to spin endlessly for ease of scrolling
  • Customizable 2 buttons
  • Optical tracking technology for superior accuracy
  • Detachable wrist rest; wired USB connection

6. J-Tech Digital Wired Ergonomic Vertical USB Mouse, Blue

What if you wanted an ergonomic vertical mouse but also something stylish? While many vertical mice tend to deliver plain appeal, this one does quite the opposite.

Its neutral handshake position utilizes the wrist and arms without triggering pain. Therefore, this product by J-Tech is highly recommended to many hardworking users/gamers.

Although it works only for right-handed people, it still is widely popular. The model is pretty big; hence, we suggest it for users with large hands. This is to ensure better support throughout the daily exertion of wrist pressure.

Now, the design features blue LED trim that lights up the outlines beautifully. It even offers an extra detachable palm rest for the convenience of the user. You can always remove it whenever preferred.

As for the DPI modes, there are three for reliable responsiveness, depending on your requirement. Plus, the forward and backward buttons in the thumb area allows optimum ease.

You can even change the functions of these buttons by using compatible software or a driver. The vertical design is a complete bliss for many carpal tunnel struggling staff and gamers.

Remember that this is a wired mouse, which some might find troublesome with a vertical mouse. However, it also means no issue with the wireless operation or sudden interruption.

Highlighted Features

  • Wider compatibility with various OS
  • 3 modes of DPI resolution; 800/1200/1600
  • 6 buttons in total; customizable thumb backward/fwd buttons
  • Includes anti-skid and sweat palm rest
  • Blue LED trim to light the outline of the mouse

7. Microsoft Sculpt Ergonomic Mouse, L6V-00001, Black

We are all aware of the vast groundbreaking success of Microsoft throughout the years. But how well can the company design an ergonomic mouse to benefit its loyal customers?

The device is pretty sleek and glory in its black, round shape, so the majority of the users had greater operational experience. It interfaces with the USB 2.0 wireless range.

We love how it maximizes the quick tracking, with the help of 2 AA alkaline batteries. Although some consumers did not favor this feature, most remarked on its easy accessibility whenever needed.

Since various people work on the PC with different timespan, the longevity of the battery life will vary. In the end, you will have to replace them anyway.

This right-hand oriented mouse offers a thumb scoop design for natural hand posture. You will find a Windows button there to access the Start Menu with one mere click.

The size of the mouse is also a concerning feature since it does not entirely cover the palm. The rotund design has the kind of angle and height that does not fit diversely.

Still, it is a good enough product for smaller hands but not something we would advise for all users. However, the standard horizontal structure will assist you in increasing workload efficiency.

Highlighted Features

  • Various gripping advantage
  • 1000 DPI sensor
  • Streamlined curves to deliver maximum comfort
  • Windows button in the thumb area for quick access
  • BlueTrack tech that combines optical and laser power

8. ZLOT Vertical Gaming Mouse, Black

Our final product is a vertical black mouse by the brand ZLOT, which is dedicated to gamers. It is affordable, cool, and ergonomic in all the ways possible.

Again, vertical mice require some getting used to, so be sure you utilize it more often for better control. Conversely, this design makes sense for all the long gaming session pro gamers.

Clearly, the hours of life-saving, enemy-dodging games will make the wrist sore and numb. That is where the ZLOT ergonomic mouse comes in. It incorporates six customizable buttons to match the game zone.

There is a mini-joystick with five rocker positions making the device an eleven-buttoned awesome device. Besides, it offers five programmable DPI sensors – 10,000 being the max!

Other features include the RGB color-changing lighting and quick responsive sensitivity. Moreover, the handshake style keeps the hand, wrist, and forearm devoid of fatigue for many hours.

These are quite important features for a gamer or a creative artist who has to work on editing software most of the time. Such a neutral position will minimize the strain and RSI related problems excellently.

The product uses wire instead of the wireless connection, but that is pretty normal for gamers. It allows them to focus on performance without getting interrupted.

All in all, the feature packing ZLOT ergonomic gaming mouse is considered one of the best among similar competitors. It will not only enhance the controlling abilities but also relieves the soreness from the wrist.

Highlighted Features

  • Vertical design with wired connectivity
  • Maximum 10,000 DPI optical sensor
  • Incorporated mini-joystick
  • 11 buttons, including the 5-position rocker
  • RGB color-changing outline lighting

Ergonomic Mouse for Carpal Tunnel’s Comparison Chart

Model Name


Maximum DPI


Fit For

LEKVEY Vertical Wireless Mouse




Right-Handed; Handshake Grip

Redragon M602 RGB Gaming Mouse




Palm Grip

Logitech MX Master 3 Mouse




Palm Grip

Jelly Comb Advanced Vertical Wireless Mouse




Right-Handed; Handshake Grip

Kensington Orbit Trackball Mouse with Scroll Ring (K72337US)




Palm Grip

J-Tech Digital Wired Ergonomic




Right-Handed; Handshake

Vertical USB Mouse





Microsoft Sculpt Ergonomic Mouse (L6V-00001)




Right-Handed; Palm, Claw, Fingertip Grip

ZLOT Vertical Gaming Mouse




Handshake Grip

Ergonomic Mouse for Carpal Tunnel Buying Guide

Take a few moments to learn the types of functionality that are best apt for your requirement. This will take you a long way in acquiring the correct model that prevents wrist strain injuries.

Ergonomic Mouse Type

There are five different structural mice to fit people with various needs. So, be aware of which one you are getting. What might feel comfortable to a user does not necessarily mean ergonomic to the other.


It is the most common form of the mouse that everyone is familiar with since the beginning. The design has a contoured dome profile for an ergonomic grip. It works with either laser or optical for movement tracking.

If you seek productivity over comfortability, this is the best option.


This style is most preferred for those suffering from carpal tunnel syndrome (CTS). It also cuts down the risk of the syndrome in advance. However, it might take some getting used to.

The main buttons are found on the side, while the holding position is in the handshake method. As a result, there is barely any twisting wrist movement.


Since the usage of this type of mouse is by rolling the ball, the base generally remains stationary. It is the rolling of the ball that controls the cursor with decent precision.

A trackball mouse does not require much space and practically involves no wrist and arm effort. This is why people with higher chances of RSI injuries benefit substantially from it.

However, it might make the ordinary cut/paste, drag/drop operations a tad complex.


It is almost like the vertical mouse structure but more radical. Many gamers prefer this design to avoid suffering from imminent tendinitis, arthritis, or carpal tunnel syndrome.

The user’s hand adopts the standard handshake position to operate a joystick mouse. It eliminates wrist pronation to a great extent.

Some might need time to adjust to this level of ergonomic mice, while others find precision issues to deal with.


Before you get any idea, this is nothing like a stylus pen. It is a regular mouse in the shape of a pen. The design allows you to operate the mouse just as you hold a pen/pencil.

This structure seemed to have helped many users who can no longer operate a standard mouse due to CTS problems.

Wireless or Wired

If we discuss the wireless option, it is obviously convenient for those who hate wire visibility everywhere. It shows a minimal, sleek, and flexible design on your desk that can be moved anyway you like.

However, they are expensive, and there is a battery life to think about. Besides, if you live in a house with kids, a child could grab the wireless USB device and lose it.

When it comes to the wired mouse, there is no fear of losing a part of the unit. The only problem is dealing with the long trail of wires.
Whatever you choose is entirely up to your liking.


This feature is an essential one to consider whenever buying the best ergonomic mouse for carpal tunnel syndrome. Different manufacturers will devise various sensors.

Nowadays, optical sensors deliver a better degree of precision. The sensitivity of a mouse is determined by the DPI (Dots per Inch). Therefore, the higher it gets, the more sensitive the mouse sensor reaches.

It allows the gamers/designers to move the cursor to a longer distance effortlessly.


Have you thought about the buttons with additional functions? We would not suggest you go overboard with them in one mouse, though.

Still, some of the extra ones can really help cut down the time as they are operational for shortcut commands. Make sure the product you choose offers some of these besides comfort.

Also, do not buy a mouse that overkills the ergonomic handling with too many buttons. That will be, in no way, convenient or beneficial.

Other models even have options to reprogram these buttons to your basic needs. This ability to store such macros is a huge advantage for creative software users.


The weight of a mouse might seem trivial to many users. It does not seem to make much difference unless you are a pro-gamer.

Even a slight difference in weight, then, can alter the scene if the game is fast-paced. So, choose according to your taste. While some like the feel of the heft, others go for the lightweight models for quick and precise movements.


Ergonomic mice are unlike conventional ones. So, expect a high price tag on these products.

But there is still a better chance of getting what you need at a reasonable price. The manufacturers always release wide ranges of similar units. It gives you the advantage of choosing something within the budget.

If you can spend more, you will achieve a higher DPI solution. Occasionally, the user can even attain a quality mouse suitable for CTS patients without wasting much!

Therefore, try to fix a specific target and then aim for a model with versatile functions.

Frequently Asked Questions

1. Can a computer mouse cause CTS?

This theory has not been proven yet. However, using of mouse and keyboard for a long while might increase the symptoms. It could worsen the current developing pain to extremity unless replacing them with ergonomic devices.

2. Is vertical mouse better for carpal tunnel syndrome?

A vertical mouse is an excellent choice for users who struggle with CTS. There are many different varieties of mice in this format for you to select from.
If you wish to avoid the CTS problem ahead of time, then a vertical mouse is the way to cut down the symptoms.

3. Are trackballs better for your wrist?

Yes, the finger-operated trackball mice offer better ergonomic features than regular ones. It is also an ideal choice for left-handed users with poor wrist posture.

Since the trackballs are suitable for ambidextrous people, they can easily get the hang of them than a vertical mouse. It helps in correcting the arm and wrist stance but might require a doctor’s consultation for a complex injury.

4. Is claw grip better than palm?

Honestly, this grip is an in-between of palm and fingertips holds. Here, only the back of your palm rests to the lower end of the mouse. The fingers form a claw shape over the buttons.

This position is somewhat beneficial for wrist movement. At the same time, long-term usage in this form might lead to index finger strain. Some may even experience fatigue, pain, and injury. So, try not to overdo it.

5. Does higher DPI mean better accuracy?

Not necessarily; However, it depends on what programs you use.

Whether you want little movement with high cursor distance coverage or more effort for the moderate range is up to you.

Remember that various applications/games might benefit from different DPI response. On the other hand, more DPI number means less wrist movement, which reduces fatigue and pain.

Final Words

We hope you can obtain the best ergonomic mouse for carpal tunnel syndrome with our help and guidance. There are still thousands of such products in the market.

However, it should not be an overwhelming job to find a particular one. The trick is to keep a set budget and have an idea of what kind of suitability you seek. Then, the next step becomes crystal clear!

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